Israeli Neuropsychologists Find the Sarcasm Lobe

In a recently published paper, The Neuroanatomical Basis of Understanding Sarcasm and Its Relationship to Social Cognition Israeli scientists described how they have unraveled the neuroanatomy of sarcasm:

The authors explored the neurobiology of sarcasm and the cognitive processes underlying it by examining the performance of participants with focal lesions on tasks that required understanding of sarcasm and social cognition. Participants with prefrontal damage (n = 25) showed impaired performance on the sarcasm task, whereas participants with posterior damage (n = 16) and healthy control (n = 17) performed the same task without difficulty. Within the prefrontal group, right ventromedial lesions were associated with the most profound deficit in comprehending sarcasm.

In addition, although the prefrontal damage was associated with deficits in theory of mind and right hemisphere damage was associated with deficits in identifying emotions, these 2 abilities were related to the ability to understand sarcasm. This suggests that the right frontal lobe mediates understanding of sarcasm by integrating affective processing with perspective taking.

Next challenge: the first sarcasm-otomy....