Update: Brian was resurrected after three weeks, saved by Stewie. (Hat tip to KS.)
But, in the episode on October 4, 2009 titled “Family Goy,” the matriarch of Seth MacFarlane’s Animated show Family Guy, Lois Griffin, learned that she is a Jew and then conducted a Seder during which Stewie recited a berakhah in perfect Hebrew.
Here's the twisted plot summary from Wikipedia:
While at the Drunken Clam, Peter falls in love with a cardboard cut out of Kathy Ireland. He takes her home and has an 'affair' with her. Soon he is caught by Lois who calls him an idiot. Peter introduces Kathy to the kids as their new mom, but after finding that Chris took her into his room, he angrily confronts her and ends up ripping her in half. He tearfully buries her in the yard and begs Lois for forgiveness. Lois forgives him and they have sex and Lois is shocked when Peter discovers a lump on her breast, causing her to go to the hospital the next day to have it tested for breast cancer. The test comes back negative, but while looking through her medical records, Dr Hartman discovers that Lois's mother is a Jewish Holocaust survivor, making Lois and her children Jewish by heritage. Barbara confirms her heritage, and Carter admits he kept it a family secret so that they could join the country club. Despite not being Jewish himself, Peter takes to it eagerly, much to Lois's frustration. That night, Peter is visited by the ghost of his stepfather, Francis, who warns him that he will go to Hell for not being Catholic. The next day, Peter decides to re-convert the family to Catholicism and becomes prejudiced against Lois' heritage, becoming anti-Semitic.
Taking advice from her mother not to let Peter suppress her identity, like her own husband did to her, Lois decides to hold a Passover Seder, which Peter tries to ruin so he can celebrate Easter. He shows up in an Easter bunny costume while drunk. Jesus appears and points out that Catholicism and Judaism are very similar. Brian then tries to interject that Islam is more or less part of that religious family, but Jesus replies "Let's not muddy things up here." He then tells Peter that he should treat people of different faiths as fairly as he wants to be treated. Peter and Lois apologize to each other, but are at a loss for what religion they should follow. Jesus tells them "Six of one; they're all complete crap." Brian, an atheist, thanks Jesus for his observation.
Meanwhile, Quagmire shows Peter and Joe a porn magazine. Peter and Joe introduce the concept of internet pornography to Quagmire, who had never heard of it before, much to their surprise and disbelief. Quagmire takes advantage of this new knowledge, and is later shown with overdeveloped muscles in his left arm after several days of masturbation.